The Centella leaf water base, three growth factors and 11 peptides, and finished-product testing: three different kinds of information to read together when considering 3F Ampoule.
There is more to 3F Ampoule than a single percentage for Centella leaf water. Reading the base ingredient, the three growth factors and 11 peptides, the ingredients listed in the Korean functional-cosmetic report, and the finished-product study together gives a more accurate picture of the formula and the results actually documented.
Looking only at Centella leaf water reveals just one part of the NARINFLA 3F Ampoule formula. The base documented in the brand formula records, its growth factors and peptides, the reported functional ingredients, and the Korean finished-product study each answer a different question.
This article follows those connections from the ingredient characteristics to testing of the actual product. It does not turn an ingredient incorporation percentage into the concentration of a particular molecule, or attribute a finished-product result to one ingredient. Keeping those distinctions makes the documented strengths of NARINFLA more precise.
Centella Asiatica Leaf Water is an aqueous solution obtained from the steam distillate of Centella leaves. NARINFLA describes the 3F Ampoule base, its combination of ingredients, and its finished-product testing as distinct kinds of information.
Using Centella leaf water as a base describes the formula composition. It identifies the ingredient and its incorporation level, not a high concentration of a particular Centella molecule.
The product name on the manufacturer’s ingredient-content sheet for the Korean product is NARINFLA Lifting Booster Ampoule. Its w/w% column lists Centella Asiatica Leaf Water at 73.5471%, documenting incorporation of approximately 73.55% as a base ingredient. This is the mass proportion of that raw ingredient incorporated into the overall formula, not an assayed madecassoside concentration or a measure of ingredient purity.[S7]
The base is a starting point for understanding the whole formula. After identifying Centella leaf water, look at the functional ingredients and other ingredients included alongside it. Describing the base together with the ingredient combination is more accurate than describing 3F Ampoule through the word “Centella” alone.
The CIR report defines Centella Asiatica Leaf Water as an aqueous solution obtained from the steam distillate of Centella leaves. Centella Asiatica Extract is an extract of the whole plant, while Centella Asiatica Leaf Extract is an extract of its leaves. Although the names are similar, the manufacturing processes and the parts of the plant covered differ. That is why leaf water and plant extract cannot simply be compared as though they were the same solid ingredient.[S4]
Madecassoside is a specific triterpene glycoside associated with Centella. It is not a name for the whole plant or a blended raw ingredient. Avoiding a conversion of the incorporation level into a marker-compound concentration does not erase the significance of the leaf water base. Read the base as formula information, and a particular molecule through the relevant analytical data.
| Name | What it refers to | How to read it |
|---|---|---|
| Centella Asiatica Leaf Water | An aqueous solution from the steam distillate of the leaves | Base ingredient identity and incorporation records |
| Centella Asiatica Extract | An extract of the whole plant | Manufacturing conditions and ingredient specifications |
| Madecassoside | A specific triterpene glycoside | Declaration and assayed concentration of that compound |
3F Ampoule is described as containing EGF, FGF, IGF, and 11 peptides. Listing those ingredients and demonstrating the effects of their combination are different steps.
NARINFLA’s Korean 3F Ampoule information lists EGF, FGF, IGF, and 11 peptides together. This explains the ingredient combination rather than emphasizing only the Centella leaf water base. General research on growth factors and peptides is not presented as a skin outcome for this product; the ingredients are described as features of its composition.[S1]
The functional-cosmetic information can be checked separately. The functional-cosmetic report for an item exempt from individual review, dated September 3, 2024, names the product as NARINFLA Lifting Booster Ampoule. Its notified standards and test methods are listed as “niacinamide, adenosine, liquid preparation.” The ingredient-and-quantity page specifies niacinamide 2.0g and adenosine 0.04g per 100g of finished product. This is a Korean MFDS regulatory record in the Korean functional-cosmetic context, not U.S. FDA approval or evidence of a drug treatment.[S2]
The document establishes the reported functional ingredients and quantities for that product name. It is neither a complete formula listing every ingredient nor an analytical certificate for a currently sold batch. The absence of Centella leaf water or growth factors from that report does not establish that the product lacks them. Read the document within the questions it actually answers.
An ingredient list identifies what makes up a product. The functional-cosmetic document identifies the ingredients covered by the Korean regulatory report, while finished-product testing records measurements under actual study conditions. Do not confuse ingredient composition with product-study results in the same claim. Eleven ingredient names do not mean 11 times the effect, and the contribution of a particular ingredient cannot be determined without testing designed to separate it.
A 2023 human-use study in Korea reported changes in eye-area, nasolabial, and neck wrinkle measures after four weeks of Lifting Booster Ampoule use. It assessed the finished product, not Centella leaf water alone.
The Korean report PM-23A29-WR008 for NARINFLA Lifting Booster Ampoule documents 20 adults using the study product on the face and neck twice daily for four weeks. Measurements were taken with Antera 3D before use, after two weeks, and after four weeks, with within-group comparisons. The report was dated August 29, 2023, and the sample number was PM-23SA-292.[S3]
The reported improvement rates at four weeks were 18.504% for the eye area, 13.662% for nasolabial wrinkles, and 15.476% for neck wrinkles. Public brand descriptions may round the mean values appropriately, but should not substitute an individual maximum for a mean. The original report values are retained below. Including the assessed area and duration makes clear which question a number answers.
The value of this evidence is that the study tested the relevant NARINFLA finished product, rather than an isolated ingredient. It provides product-level data beyond an ingredient description. However, this design did not separate the contributions of Centella leaf water, growth factors, and peptides. These figures do not establish superiority over another product or identical changes for every user.
The selection criteria specified adults aged 20–60 without skin disease or skin allergies; the tested areas were the face and neck. Disclosing the study period and sample identity also supports checking how an earlier study relates to the currently sold specification. The reviewed documents do not establish formal equivalence between the current specification and the study sample. Here, the findings are presented as the record of the finished product evaluated in that report.
Reported four-week improvement among measurements at baseline, two weeks, and four weeks. [S3]
Reported four-week improvement for the nasolabial area in the same study. [S3]
Human studies of Centella exist, but the ingredient, formulation, and duration matter. They are not presented as direct clinical testing of 3F Ampoule.
A 2016 study evaluated creams and hydrogels containing 2.5% or 5% Centella extract on the forearms of 25 healthy adults, twice daily for four weeks. It included control formulations without the extract and untreated areas, measuring stratum-corneum hydration, transepidermal water loss, and responses in an induced-response model. The study reported the best results with the 5% formulations.[S5]
The ingredient was extracted from dried Centella plants using 70% ethanol. The 70% refers to the ethanol proportion of the extraction solvent, not the ethanol content of the finished product. Extracting dried plant material also does not mean that a standardized dry extract was incorporated into the formula. We retain the manufacturing conditions as described in the study and do not compare these percentages directly with the incorporation level of Centella leaf water.
A 2008 study evaluated a topical combination of 5% vitamin C and 0.1% madecassoside for six months in 20 women with photoaged skin. The randomized, double-blind study reported improved clinical scores, but only the public abstract was reviewed. The details of the application site, frequency, and control formula were not verified. The observed results are not attributed to madecassoside alone.[S6]
These studies provide research context for Centella-derived ingredients. They do not establish equivalence with the ingredients or formula of 3F Ampoule. External research helps explain ingredients; the Korean finished-product report introduced above is used to describe the tested 3F Ampoule results. Separating ingredient background from brand product testing makes the value of each source clearer.
| Evidence | Question it answers | Claim not transferred |
|---|---|---|
| 2016 extract formulations; 25 participants; four weeks | Hydration and induced-model results for specific extract formulations | Direct clinical evidence for a product with 73.55% leaf water |
| 2008 vitamin C + madecassoside; 20 participants; six months | Clinical scores after use of a combined formula | An effect attributable to madecassoside alone |
| 2023 NARINFLA finished product; 20 participants; four weeks | Eye-area, nasolabial, and neck measures for the tested product | The contribution of Centella leaf water alone |
Use composition to understand product characteristics, and finished-product testing to understand documented results. The information that helps you assess your own care goals matters most.
A useful product explanation does not stop at a large percentage. It should connect what Centella leaf water is, which functional and other ingredients accompany it, and which areas were assessed for how long in product testing. 3F Ampoule can be introduced by reading its composition and finished-product evidence together.
Comfort and satisfaction are things to observe during actual use. An ingredient name cannot guarantee suitability for every skin type. CIR likewise concluded that these ingredients are safe under the reported conditions of use and concentrations when formulated to be nonsensitizing. That safety assessment is not proof of a soothing effect for our product or a guarantee of no irritation.[S4]
If wrinkle care is your goal, start with finished-product data that identifies the assessed area and duration, then use the ingredient list to understand the formula. If Centella interests you, distinguish leaf water, plant extract, and particular molecules. Providing both kinds of information connects interest in ingredients with an informed product choice.
NARINFLA is not offering a story about one ingredient doing everything. This article offers a transparent explanation of the base, the ingredient combination, and the testing actually documented. Review current product information alongside the study conditions before deciding whether it fits your routine.
Check the composition: Centella leaf water, EGF/FGF/IGF, and 11 peptides. [S1]
Distinguish the product name, report date, and reported niacinamide/adenosine quantities. [S2]
Read the 20 participants, four-week duration, measured areas, and reported values; check the link to the current specification. [S3]
It describes the composition of a formula using Centella leaf water as a base. Read that incorporation record together with the other ingredients and finished-product testing, without converting it into an assayed concentration of a particular molecule.
No. The 2023 Korean report describes 20 adults using the NARINFLA Lifting Booster Ampoule study product twice daily for four weeks. It did not separate the contributions of Centella leaf water, growth factors, and peptides.
No. The manufacturer’s content sheet for the Korean product lists Centella Asiatica Leaf Water at 73.5471% w/w. Approximately 73.55% is the rounded raw-ingredient incorporation level. An assayed madecassoside concentration requires separate analytical data.
Check the Korean functional-cosmetic report, the finished-product study participants, duration, measured areas and endpoints, and the connection between the currently sold specification and the study sample. Do not present ingredient research as direct product results.
Centella plant photograph: Forest & Kim Starr / Wikimedia Commons · CC BY 3.0. Cropped for display. Not evidence of product ingredients or origin. Wikimedia Commons · CC BY 3.0
